Approved Study Database
| Ref. No. | Scientific Title | Principal investigator |
|---|---|---|
| 2015.040 | Progression of glucose intolerance, cardiometabolic risk factors and subclinical atherosclerosis in Chinese women with Polycystic Ovary Syndrome | Prof. MA Ronald |
| 2015.316 | Maternal exposure to Perfluorooctane sulfonate (PFOS) and the risk of childhood obesity and metabolic abnormalities in the offspring- analysis of a longitudinal birth cohort |
Prof. MA Ronald 馬青雲 |
| 2016.103 | Unraveling the link between maternal hyperglycaemia and childhood obesity: Genome-wide methylation analysis in a prospective cohort of untreated gestational diabetes |
Prof. MA Ronald 馬青雲 |
| 2016.328 | Epigenetic markers of type 2 diabetes and diabetic complications |
Prof. MA Ronald 馬青雲 |
| 2013.432 | Identification of epigenetic markers in offspring exposed to maternal hyperglycaemia | Prof. MA Ronald |
| 2013.447 | Developing a Metagenomic Next-Generation Sequencing Software Platform for Discovering Biomarkers with Application to Obesity and Type 2 Diabetes | Prof. MA Ronald |
| 2015.473 | Identification of genetic loci for birthweight and cardiometabolic traits in childhood |
Prof. MA Ronald 馬青雲 |
| 2008.518 | Progression of cardio-metabolic risk factors in Chinese women with Polycystic Ovary Syndrome | Prof Ma Ronald |
| 2013.042 | Identification of clinical and genetic predictors of hyperglycaemia and impaired beta-cell function in Chinese children- an analysis using mother-offspring pairs | Prof. MA Ronald |
| 2011.302 | Identificatin and large-scale replication of genetic predictors of diabetic kidney disease and diabetic retinopathy in the Chinese population | Prof Ma Ronald |
| 2013.251 | An integrated trans-omics approach to diabetic cardio-renal complications: from novel discoveries to personalized medicine - Substudy 1: Transcriptome analysis of diabetic kidney disease | Prof. MA Ronald |
| 2011.047 | Identification of genetic variants assocaited with atrial fibrillation and its effect in subjects with diabetes | Prof Ma Ronald |
| 2011.118 | Genetic determinants of obesity and cardiometabolic traits in Chinese adolescents | Prof. Ma Ronald |
| 2008.519 | The role of neurohormonal dysregulation in the transgenerational effects of maternal diabetes | Prof Ma Ronald |
| 2011.354 | Identification of epigenetic markers associated with maternal diabetes and obesity | Prof. MA Ronald |
| 2013.187 | An integrated trans-omics approach to diabetic cardio-renal complications: from novel discoveries to personalized medicine | Prof. MA Ronald |
| 2013.304 | An integrated trans-omics approach to diabetic cardio-renal complications: from novel discoveries to personalized medicine Substudy 2: The Hong Kong Diabetes Biobank | Prof. MA Ronald |
| 2022.475 | Translating multi-omic discoveries to transform diabetes care and reduce diabetic complications Substudy 1: A randomized controlled trial to evaluate the clinical utility of communicating polygenic risk scores in diabetes | Prof. MA Ronald |
| 2018.357 | Comprehensive evaluation and mechanism investigation of the PAX4 gene R192H variant on diabetes, diabetes-related traits and diabetic complications |
Prof. MA Ronald 馬青雲 |
| 2015.458 | The effect of imagery and rumination on depression: a mediation and intervention study |
Ms. MA Olivia 馬婉婷 |
| 2015.241 | A Transdiagnostic Anger Management Program for Adult Psychiatric Inpatient |
Ms. MA Olivia 馬婉婷 |
| 2022.043 | Effects of a structured Tai Chi program on improving physical activity level, exercise self-efficacy, and health outcomes among pregnant women: A randomised controlled trial |
Ms. MA Nan 马楠 |
| 2013.407 | Pharmacokinetic study of once-daily formulation of Tacrolimus (Advagraf_) in Chinese kidney transplant patients | Dr Ma King Wing, Terry |
| 2023.153 | Mitochondrial disease related mortality - evaluation of a large international cohort | Dr. MA Kam Hung |
| 2012.321 | An opinion Survey among frail elderly patients and their carers regarding their opinion about self-financed community care services | Dr MA HON MING |
| 2009.415 | A Cohort Study on the Clinical Outcomes of Elderly Patients Admitted for Community Acquired Pneumonia (CAP) | Dr. MA Hon Ming |
| 2017.282 | Mindfulness-based cognitive therapy for community-dwelling adults with anxiety symptoms: An exploration of efficacy and cognitive mechanism |
Miss MA Duan Yang 馬端陽 |
| 2011.506 | Transvaginal ultrasound probe contamination by the Human Papillomavirus in the Emergency Department | Dr. MA Christine Shuk Ting |
| 2012.052 | An evaluation on the effectiveness, acceptability and pricing of annual complication assessment for people with diabetes mellitus in the Hong Kong Community | Prof Ma Ching-wan, Ronald |
| 2010.466 | SAVOR Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus A Multicenter, Randomised, Double-Blind, Placebo-Controlled Phase IV Trial to Evaluate the Effect of Saxagliptin on the Incidence of Cardiovascular Death, Myocardial Infarction or Ischaemic Stroke in Patients with Type 2 Diabetes | Professor Ma Ching Wan Ronald |
| 2025.419 | EASi-PROTKT™ - A Phase III double-blind, randomised, parallel-group superiority trial to evaluate efficacy and safety of the combined use of oral vicadrostat (BI 690517) and empagliflozin compared with placebo and empagliflozin in participants with type 2 diabetes, hypertension and established cardiovascular disease |
Prof. MA Ching Wan 馬青雲 |
| 2025.544 | A Randomised, Double-blind, Placebo-controlled, Multi-centre, Sequential Phase II, and Phase III Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of AZD0780 Administered for up to 52 Weeks in Participants with Dyslipidaemia (AZURE-CHINA) |
Prof. MA Ching Wan 馬青雲 |
| 2010.473 | An East Asian phase I, multicenter, open-label, dose-escalation study of oral LDE225 in patients with advanced solid tumors | Associate Prof. Ma Buig Yue Brigette |
| 2010.251 | Uncontrolled, open-label, non-randomized, phase 1 study to investigate the pharmacokinetics, safety, tolerability, and efficacy of BAY 73-4506 in Chinese patients with advanced, refractory solid tumors | Associate Professor Ma Brigette Buig-Yue |
| 2020.054 | A phase I/Ib, open-label, multi-center, study of KAZ954 as a single agent and in combination with Spartalizumab, NZV930 and NIR178 in patients with advanced solid tumors |
Prof. MA Brigette Buig Yue 馬碧如教授 |
| 2019.153 | A Phase I/Ib, open-label, multi-center study of NZV930 as a single agent and in combination with PDR001 and/or NIR178 in patients with advanced malignancies |
Prof. MA Brigette Buig Yue 馬碧如教授 |
| 2017.540 | A phase I/II study of safety and efficacy of ribociclib (LEE011) in combination with trametinib (TMT212) in patients with metastatic or advanced solid tumors |
Prof. MA Brigette Buig Yue 馬碧如教授 |
| 2014.357 | A PHASE Ib STUDY OF THE SAFETY AND PHARMACOLOGY OF ATEZOLIZUMAB (ANTI-PD-L1 ANTIBODY) ADMINISTERED WITH ERLOTINIB OR ALECTINIB IN PATIENTS WITH ADVANCED NON−SMALL CELL LUNG CANCER | Prof. MA Brigette Buig Yue |
| 2015.455 | A phase II, open-label, randomized controlled study of PDR001 in patients with moderately differentiated/undifferentiated locally advanced recurrent or metastatic nasopharyngeal carcinoma who progressed on standard treatment |
Prof. MA Brigette Buig Yue 馬碧如教授 |
| 2016.385 | A phase I/II, multicenter, open-label study of MAK683 in adult patients with advanced malignancies |
Prof. MA Brigette Buig Yue 馬碧如教授 |
| 2015.442 | A Phase I/II, open label, multicenter study of the safety and efficacy of LAG525 single agent and in combination with PDR001 administered to patients with advanced malignancies |
Prof. MA Brigette Buig Yue 馬碧如教授 |
| 2016.443 | A PHASE III, OPEN LABEL, MULTICENTER, THREE-ARM, RANDOMIZED STUDY TO INVESTIGATE THE EFFICACY AND SAFETY OF COBIMETINIB PLUS ATEZOLIZUMAB AND ATEZOLIZUMAB MONOTHERAPY VS. REGORAFENIB IN PATIENTS WITH PREVIOUSLY TREATED UNRESECTABLE LOCALLY ADVANCED OR METASTATIC COLORECTAL ADENOCARCINOMA |
Prof. MA Brigette Buig Yue 馬碧如 |
| 2017.404 | ElevatION: CRC-101: A Phase Ib study of PDR001 in combination with bevacizumab and mFOLFOX6 as first line therapy in patients with metastatic MSS colorectal cancer |
Prof. MA Brigette Buig Yue 馬碧如教授 |
| 2014.662 | A phase Ib dose-finding study of BYL719 plus everolimus and BYL719 plus everolimus plus exemestane in patients with advanced solid tumors, with dose-expansion cohorts in renal cell cancer (RCC), pancreatic neuroendocrine tumors (pNETs), and advanced breast cancer (BC) patients. | Prof. MA Brigette Buig Yue |
| 2017.357 | A Phase Ib/II, open label, multicenter study of MCS110 in combination with PDR001 in patients with advanced malignancies |
Prof. MA Brigette Buig Yue 馬碧如教授 |
| 2017.247 | Phase Ib study of PDR001 in combination with regorafenib in adult patients with previously treated metastatic microsatellite stable (MSS) colorectal cancer |
Prof. MA Brigette Buig Yue 馬碧如教授 |
| 2025.375 | tReatment Individualisation By EBV stratificatiON in nasopharyngeal carcinoma: an umbrella platform study (RIBBON-Umbrella) | Prof. MA Brigette Buig Yue |
| 2025.199 | A Phase I/II, Open-Label, Multicenter Study of ALE.P02 (Claudin-1 Targeted Antibody-Drug Conjugate) as a Monotherapy or in Combination with Pembrolizumab (anti-PD-1 antibody) in Adult Patients with Selected Advanced or Metastatic CLDN1+Squamous Solid Tumors | Prof. MA Brigette Buig Yue |
| 2025.202 | A PHASE I DOSE ESCALATION AND EXPANSION STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PRELIMINARY CLINICAL ACTIVITY OF RO7673396 AS A SINGLE AGENT AND IN COMBINATION WITH OTHER ANTICANCER THERAPIES IN PATIENTS WITH ADVANCED SOLID TUMORS HARBORING RAS MUTATION(S) | Prof. MA Brigette Buig Yue |
| 2025.386 | A Phase 3, Randomized, Open-label, Multicenter Clinical Study to Evaluate the Safety and Efficacy of MK-1084, Cetuximab, and mFOLFOX6 versus mFOLFOX6 With or Without Bevacizumab as First-line Treatment of Participants With KRAS G12C-mutant, Locally Advanced Unresectable or Metastatic Colorectal Cancer (KANDLELIT-012) | Prof. MA Brigette Buig Yue |
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