Approved Study Database
| Ref. No. | Scientific Title | Principal investigator |
|---|---|---|
| 2025.636 | A Multi-Country Observational Chart Review Study to Characterize Treatment Patterns and Clinical Outcomes among Patients with Resectable Gastric or Gastroesophageal Junction Cancer | Prof. YEO Winnie |
| 2025.635 | Development of a risk evaluation model for bone scintigraphy triage based on machine learning and artificial intelligence and large language models. | Dr. Wong Matthew Lun |
| 2025.634 | A territory-wide retrospective study comparing between transrectal versus transperineal prostate biopsy |
Dr. LIU Alex Qinyang Chi Fai NG |
| 2025.633 | Long-term Outcomes of Prostatic Artery Embolization (PAE) – A retrospective cohort study | Dr. CHIU Peter Ka Fung |
| 2025.632 | The prognostic impact of change in serum alpha-fetoprotein level for recurrent hepatocellular carcinoma after hepatectomy: a retrospective study | Dr. LEE Kit Fai |
| 2025.631 | AI Screening of Head CT scans for Cognitive Decline | Dr. Abrigo Jill |
| 2025.630 | Left Atrial Appendage Occlusion in Dialysis Patients with Atrial Fibrillation: A Multicentre Pilot Study | Dr. SO Kent Chak Yu |
| 2025.629 | TulmiSTAR-02: A two-part Phase I dose escalation study of tulmimetostat (DZR123) in combination with darolutamide or abiraterone followed by open-label, randomized, Phase II dose expansion study to assess the safety and efficacy of tulmimetostat in combination with darolutamide versus darolutamide alone in patients with metastatic hormone-sensitive prostate cancer | Prof. NG Chi Fai |
| 2025.628 | A Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Clinical Activity of GSK5764227 as Monotherapy and in Combination in Participants with Advanced Solid Tumors | Dr. LOONG Herbert Ho Fung |
| 2025.627 | A Randomized, Phase 2/3 Study Comparing Navlimetostat (BMS-986504) in Combination with Nab-paclitaxel and Gemcitabine versus Placebo in Combination with Nab-paclitaxel and Gemcitabine in Participants with Untreated Metastatic Pancreatic Ductal Adenocarcinoma Harboring Homozygous MTAP Deletion | Prof. CHAN Stephen Lam |
| 2025.626 | A Randomized Phase 2/3 Study of BMS-986504 in Combination with Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants with Homozygous MTAP Deletion | Dr. LI Siu Ching |
| 2025.625 | Smart Bracing for Adolescent Idiopathic Scoliosis: A Pilot Study of Real-Time Continuous Monitoring via Fiber Optic FBG Sensor | Dr. LAU Adam Yiu Chung |
| 2025.624 | Quantitative measurement of plasma and urine MTB cell-free DNA level in diagnosing TB and treatment monitoring | Prof. CHAN Ken Ka Pang |
| 2025.623 | Can Alpha-ketoglutarate (AKG) Ameliorate Sarcopenia? A Randomized, Double-Blind, Placebo-Controlled Trial | Dr. LIU Chaoran |
| 2025.622 | Effect of an internet-based dialectical behaviour therapy-informed skills training for reducing alcohol consumption and improving psychological distress of adult drinkers: A randomised controlled trial | Prof. Ho Long Kwan |
| 2025.621 | Novel microbiome signatures for the prediction of dementia-first versus parkinsonism-first conversion in REM sleep behavior disorder | Dr. HUANG Bei |
| 2025.620 | A RETROSPECTIVE STUDY ON EFFICACY AND TOLERABILITY OF TRASTUZUMAB DERUXTECAN FOR ADVANCED BREAST CANCER PATIENTS WITH HER2-POSITIVE, HER2-LOW OR HER2-ULTRALOW DISEASE | Prof. YEO Winnie |
| 2025.619 | Review of Clinical Outcomes of Structured Non-Surgical Treatment Programme for Knee Osteoarthritis in Prince of Wales Hospital | Ms. Li Man Kuen |
| 2025.618 | Evaluation knowledge level of ACLS among HKFSD paramedics |
Mr. Wong Kwan Tung 黃鈞彤 |
| 2025.617 | Effectiveness of a nurse-led WeChat-based multi-component intervention on body weight in colorectal cancer patients undergoing chemotherapy: a randomised controlled study |
Ms. CAO Yu 曹玉 |
| 2025.616 | The Effects of Transcranial Temporal Interference Stimulation to the Amygdala on Emotion Regulation and Conflict Resolution | Dr. LIU Xiaonan |
| 2025.615 | Telehealth-supported discharge programme on health outcomes among frail older adults: A pilot randomized controlled trial | Prof. XIAO Sarah |
| 2025.614 | 7-year prospective study of psychiatric patients with comorbid REM sleep behavior disorder: diagnostic stability and progression of prodromal features of α- synucleinopathy | Prof. WING Yun Kwok |
| 2025.613 | Effects of Ten-Week Oral Nicotinamide Riboside Supplementation with Aerobic Exercises on Blood Pressure in Post-menopausal Women with Elevated/Stage I Hypertension | Prof. Yu Angus Pak Hung |
| 2025.612 | A pilot experimental study of acoustic stimulation in enhancing slow wave sleep to improve sleep quality in insomnia disorder |
Dr CHEN XIE 陈勰 |
| 2025.611 | AFFIRM: A Randomized, Double-Blind, Placebo-Controlled, Study to Evaluate the Effect of Seladelpar on Clinical Outcomes in Patients with Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis | Prof. Lai Jimmy Che To |
| 2025.610 | From Benchside to Clinical: Identifying the Probiotic to Treat Sarcopenia in Older Adults for Healthy Aging | Prof. WONG Ronald Man Yeung |
| 2025.609 | A prospective randomised study to compare patient satisfaction following the treatment of lower caliceal stones using shockwave lithotripsy or retrograde intrarenal surgery | Prof. NG Chi Fai |
| 2025.608 | Beamion LUNG-3: A randomized, controlled, multi-center trial evaluating zongertinib as an adjuvant monotherapy compared with standard of care in patients with early-stage, resectable non-small cell lung cancer (Stage II-IIIB) harboring tyrosine kinase domain activating HER2 mutations | Dr. LOONG Herbert Ho Fung |
| 2025.607 | Effectiveness of Haptik App Feedback on Apple Watch in improving Cardiopulmonary Resuscitation (CPR) Quality in Paramedics: A Randomized Crossover Trial |
Mr. CHAN CHI YIP 陳智業 |
| 2025.606 | Natural History of Patients with Staghorn Stones in Hong Kong over 17 years: A Real-World Cross Sectional Observational Study | Dr. LIU Qinyang |
| 2025.605 | A Phase I/II, Open-label, Multicenter Study of ALE.P03 (Claudin-1 Targeted Antibody-drug Conjugate) as a Monotherapy in Adult Patients with Selected Advanced or Metastatic CLDN1+ Solid Tumors | Prof. CHAN Stephen Lam |
| 2025.604 | Clamp catheter versus snare for Inferior Vena Cava filter retrieval: a single centre experience | Dr. LAW Wing Chung |
| 2025.603 | Cardio-Oncology in Prostate Cancer: Building a Territory-Wide Cohort with Risk Prediction and Target Trial Emulation framework for cardio-protective strategies | Dr. Liu Qinyang |
| 2025.602 | Dynamic changes of serum albumin-to-globulin ratio predict major adverse cardiovascular events in prostate cancer patients undergoing androgen deprivation therapy | Prof. NG Chi Fai |
| 2025.601 | An international multicenter registry study for young-onset colorectal cancer in East and Southeast Asia | Prof. Ng Simon |
| 2025.600 | Predictive modelling of urological outcomes based on retrospective routine nurse-led clinic assessments | Prof. LIU Qinyang |
| 2025.599 | Erectile dysfunction and major adverse cardiovascular events in prostate cancer | Prof. NG Chi Fai |
| 2025.598 | Epidemiological Trend and Projections on Disease Burden in Hong Kong | Prof. HUANG Junjie |
| 2025.597 | Construction of diagnostic and predictive models for cirrhosis patients with complications of liver disease | Prof. Wong Grace |
| 2025.596 | Deciphering the role of ADAT2-mediated transfer RNA A-to-I modification in colorectal tumorigenesis and chemoresistance |
Dr. WONG Chi Chun Chi Chun Wong |
| 2025.595 | The level of knowledge, attitude, and practice (KAP) to stroke management among undergraduate nursing students in Hong Kong: A cross-sectional survey |
Miss Lo Tsz Yau 盧芷柔 |
| 2025.594 | Phase I Clinical Trial of Low and High Dose Allogeneic Mesenchymal Stromal Cell Treatment for Knee Osteoarthritis |
Prof. ONG Michael Tim Yun 王添欣 |
| 2025.593 | Comparison of Vacuum Mattresses and Spinal Long Boards in Wilderness simulation | Mr. CHING SZE YU |
| 2025.592 | Evaluation of airway management by first responders (fire personnel of the Hong Kong Fire Services Department) on out-of-hospital cardiac arrest patients in Hong Kong: a crossover study | Mr. WU Ka yiu |
| 2025.591 | Safety and Feasibility of Custom Engineered Curved Scissors for Nasal Surgery |
Dr. YEUNG David David Chun Man Yeung |
| 2025.590 | A Phase III, Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durvalumab Compared with Investigator’s Choice of Chemotherapy (Paclitaxel, Nab-paclitaxel or Gemcitabine + Carboplatin) in Combination With Pembrolizumab in Patients with PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05) | Prof. YEO Winnie |
| 2025.589 | A Phase 3, Randomized, Open-label, Study to Compare the Efficacy and Safety of Adjuvant MK-2870 in Combination with Pembrolizumab (MK-3475) Versus Treatment of Physician’s Choice (TPC) in Participants With Triple-Negative Breast Cancer (TNBC) Who Received Neoadjuvant Therapy and Did Not Achieve a Pathological Complete Response (pCR) at Surgery | Prof. YEO Winnie |
| 2025.588 | Exploring the Protective Role of Bacteroides intestinalis against Metabolic Dysfunction-Associated Steatotic Liver Disease | Prof. ZHANG Xiang |
| 2025.587 | Satisfaction, Visual and Refractive Outcomes of Bilateral Cataract Extraction with Implantation of Light Adjustable Intraocular Lenses (IOL) | Prof. THAM Clement Chee Yung |
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