Approved Study Database
| Ref. No. | Scientific Title | Principal investigator |
|---|---|---|
| 2010.498 | Dose-Ranging Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Pegylated Interferon Lambda (BMS-914143) Monotherapy in Interferon-Naive Patients with Chronic Hepatitis B Virus Infection who are HBeAg-positive | Prof CHAN Lik Yuen, Henry |
| 2011.429 | Alcohol Related Liver Damage in Hong Kong | Prof. Chan Lik Yuen, Henry |
| 2008.367 | Development of a Non-Invasive Algorithm for Advanced Liver Fibrosis in Chronic Hepatitis B | Prof. Chan Lik Yuen, Henry |
| 2010.286 | Efficacy of entecavir or tenofovir in chronic hepatitis B patients with lamivudine resistance suboptimal virological response to adefovir | Prof Chan Lik Yuen, Henry |
| 2012.046 | Serum hepatitis B surface antigen levels to guide the stopping of entecavir in HBeAg-negative chronic hepatitis B | Prof Chan Lik Yuen Henry |
| 2012.536 | A multicenter open-label study to evaluate the safety and efficacy of PEG-Intron™ versus PEGASYS™ in subjects with HBeAg positive chronic hepatitis B and HBeAg negative chronic hepatitis B | Prof. Chan Lik Yuen Henry |
| 2013.115 | An Open Label, Phase 2a, Single-Arm Study of the Antifibrotic Activity of FG-3019 in Subjects with Advanced Liver Fibrosis due to Chronic Hepatitis C Infection (HCV) | Prof Chan Lik Yuen Henry |
| 2017.328 | A PHASE I, SPONSOR-OPEN, INVESTIGATOR-BLINDED, SUBJECT-BLINDED, MULTI-CENTER, PLACEBO-CONTROLLED STUDY TO EVALUATE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF ORAL ADMINISTRATION OF RO7020531: (1). SINGLE AND MULTIPLE ASCENDING DOSES IN HEALTHY MALE AND FEMALE SUBJECTS; (2). 6-WEEK TREATMENT OF PATIENTS WITH CHRONIC HEPATITIS B VIRUS INFECTION |
Prof. CHAN Lik Yuen 陳力元 |
| 2016.089 | A MULTIPLE-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, SINGLE-ASCENDING DOSE AND MULTIPLE-ASCENDING DOSE, ADAPTIVE PARALLEL STUDY TO INVESTIGATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF RO7020322 FOLLOWING ORAL ADMINISTRATION IN HEALTHY SUBJECTS AND CHRONIC HEPATITIS B PATIENTS |
Dr. CHAN Lik Yuen 陳力元 |
| 2015.124 | A MULTIPLE-CENTER, RANDOMIZED, PARTIALLY DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO INVESTIGATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS AND ANTIVIRAL EFFECTS OF 12-WEEK TREATMENT WITH RO6864018 IN VIROLOGICALLY SUPPRESSED PATIENTS WITH CHRONIC HEPATITIS B VIRUS INFECTION |
Prof. CHAN Lik Yuen 陳力元 |
| 2017.177 | A Phase 3, Randomized, Double-Blind Study to Evaluate the Efficacy and Safety of Switching from Tenofovir Disoproxil Fumarate (TDF) 300 mg QD to Tenofovir Alafenamide (TAF) 25mg QD in Subjects with Chronic Hepatitis B who are Virologically Suppressed |
Dr. CHAN Lik Yuen 陳力元 |
| 2010.579 | Functional roles of an orphan nuclear receptor Tailless TLX in advanced prostate cancer | Prof CHAN Leung Franky |
| 2008.168 | A Functional Study of An Epithelial-Mesenchymal Transition Regulatory Transcription Factor Snail in Prostate Cancer | Prof. Chan Leung Franky |
| 2014.626 | Evaluation of the psychometric properties of the Chinese version of the Multidimensional Fatigue Inventory among community dwelling older adults with multicomorbidities by a non-experimental, prospective, descriptive, correlation study design | Mr Chan Leong Tat |
| 2015.512 | Effect of a structured aerobic exercise programme in managing fatigue among community dwelling older adults with multicomorbidities by a prospective randomized controlled trial |
Mr. CHAN Leong Tat 陳亮達 |
| 2014.410 | End-of-life decisions in Neonatal Intensive Care Unit: A Retrospective Analysis of Modes of Deaths in the NICU | Dr CHAN Lawrence Chi Ngong |
| 2019.175 | Variation in intensive care practices for moderate to severe traumatic brain injury |
Dr. CHAN Lawrence Chi Ngong 陳子昂 |
| 2017.533 | Prevalence of neuromyelitis optica in Hong Kong |
Dr. CHAN Larry Wai Lun 陳偉麟 |
| 2026.565 | Study on the outcome of lenvatinib treated in patients’ journey of hepatocellular carcinoma | Dr. Chan Landon Long |
| 2026.420 | IMPACT 31: A Randomized Open-label, Multi-center, Phase II Adjuvant Study of a Personalized Neoantigen DNA Vaccine (GNOS-PV02) and Plasmid encoded IL-12 (INO-9012) versus Active Surveillance in Subjects with High-Risk Hepatocellular Carcinoma | Dr Chan Landon Long |
| 2026.595 | A PHASE 2, RANDOMIZED, OPEN-LABEL STUDY OF VVD-133214 IN COMBINATION WITH PEMBROLIZUMAB COMPARED TO PEMBROLIZUMAB MONOTHERAPY IN PARTICIPANTS WITH ADVANCED COLORECTAL ADENOCARCINOMA (CRC) HARBORING MICROSATELLITE INSTABILITY (MSI) AND/OR DEFICIENT MISMATCH REPAIR (DMMR) | Dr. Chan Landon Long |
| 2024.311 | Stereotactic Body Radiotherapy with Immunotherapy (Atezolizumab plus Bevacizumab) in Patients with Advanced HCC and Major Portal Vein Tumour Thrombosis |
Dr. CHAN Landon Stephen Lam CHAN |
| 2024.326 | Impact of Radiotherapy on the Dynamic Changes of Circulating Cell-free DNA in Patients with Hepatocellular Carcinoma | Dr. CHAN Landon |
| 2011.145 | The use of circulating methylated RASSF1A in prognostication and monitoring of treatment response for inoperable hepatocellular carcinoma | Dr. Chan Lam, Stephen |
| 2010.563 | An open-label, randomized, multi-center, phase II study to compare the safety and efficacy of TKI258 versus sorafenib as first-line treatment in adult patients with advanced hepatocellular carcinoma | Assistant Professor Chan Lam, Stephen |
| 2010.564 | A Randomized Phase III study of Oxaliplatin (Eloxatin) and Capecitabine on top of Sorafenib versus Sorafenib alone as first-line palliative treatment in advanced hepatocellular carcinoma patients ineligible for curative resection or local treatment | Prof Chan Lam |
| 2025.833 | Clinical Utility of the Treatment-related Toxicity Risk Model (TRTRM) in Older Patients with Cancer: a Randomised Controlled Trial | Dr. Chan Lam |
| 2015.459 | A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Enzalutamide in Subjects with Advanced Hepatocellular Carcinoma |
Prof. CHAN Lam 陳林 |
| 2016.085 | A Phase 3 Randomized, Open-Label Study Comparing Pexa-Vec (Vaccinia GM CSF / Thymidine Kinase-Deactivated Virus) Followed by Sorafenib Versus Sorafenib in Patients with Advanced Hepatocellular Carcinoma (HCC) Without Prior Systemic Therapy |
Dr. CHAN Lam 陳林 |
| 2011.529 | Effectiveness of warm lignocaine in reducing infiltration pain during digital nerve block injection: A randomized controlled trial. | Ms CHAN LAI MAN |
| 2008.430 | Comparison of the Accuracy of Bernese Ankle Rules and Ottawa Ankle Rules in Ruling Out Ankle and Mid-Foot Fractures of Adults in Twisting Ankle and Foot Injury. A Prospective Cross Sectional Study | Ms CHAN LAI MAN |
| 2012.508 | Psychiatric and physical comorbidities among primary care insomniacs in Hong Kong | Dr. Chan Kwok Keung |
| 2025.749 | Comparing diagnostic performance of 3D T1 VIBE MR sequence to CT for the detection of radiographically occult fractures of the hip and pelvis | Dr. CHAN Kwan Kit |
| 2010.021 | Investigation into the association between the presence of methylate tumour suppressor gene sequences in serum and the risk of developing hepatocellular carcinoma in chronic hepatitus B carriers | Prof CHAN Kwan Chee Allen |
| 2008.166 | Investigationof the Genomic Representation of Fetal DNA in the Plasma of Pregnant Women | Prof CHAN Kwan Chee Allen |
| 2008.024 | Investigation on the Long and Short-term Variations of Plasma Epstein-Barr Virus (EBV) DNA in Healthy Subjects | Prof Chan Kwan Chee Allen |
| 2026.574 | Among women who have undergone mastectomy (with or without reconstruction), does nurse-led 3D Nipple-Areola Complex (NAC) tattooing improve patient-reported outcomes—assessed using the BREAST-Q Reconstruction Module—such as aesthetic satisfaction and quality of life, within 6 months? | Ms. CHAN KOVIE KA WING |
| 2013.284 | Detection of Cerebral Autoregulation in Patients witih Supertentorial Intracerbral Hemorrhage Using Transcranial Doppler Ultrasonography | DR CHAN KIT YING |
| 2013.148 | Retrospective study on the management in children with anorectal malformation | Dr Chan Kin Wai Edwin |
| 2012.433 | Retrospective study on the incidence of cleft palate and the outcome of cleft palate repair | Dr Chan Kin Wai Edwin |
| 2014.152 | Retrospective study on the outcome of Kasai portoenterostomy in infant with biliary atresia | Dr Chan Kin Wai Edwin |
| 2023.666 | A survey on the practice and interpretation of various diagnostic tests for tuberculous pleuritis among respiratory physicians | Prof. CHAN Ken Ka Pang |
| 2024.232 | Prospective study on detection and prediction of clinically significant pneumothorax after image-guided transthoracic lung biopsy | Prof. CHAN Ken Ka Pang |
| 2025.155 | Diagnostic utility of pleural infection-specific multiplex PCR panel to identify causative microorganisms in pleural infection | Prof. CHAN Ken Ka Pang |
| 2024.310 | Chest Radiograph Research Repository | Prof. CHAN Ken Ka Pang |
| 2024.542 | Liquid biopsy by measuring pleural fluid Mycobacterium tuberculosis cell-free DNA (MTB cfDNA) level to diagnose tuberculous pleuritis in a real-world setting | Prof. CHAN Ken Ka Pang |
| 2025.740 | Prospective Evaluation of Plasma Mycobacterium tuberculosis cell-free DNA Sequencing as a Non-Invasive Alternative to Bronchoscopy for Diagnosing Pulmonary Tuberculosis | Prof. CHAN Ken Ka Pang |
| 2025.624 | Quantitative measurement of plasma and urine MTB cell-free DNA level in diagnosing TB and treatment monitoring | Prof. CHAN Ken Ka Pang |
| 2025.467 | Multidimensional correlation between histolopathological results and clinical data for cancer prognostication | Prof. CHAN Ken Ka Pang |
| 2025.267 | A pilot randomised study comparing the clinical efficacy of stopping air leak by talc pleurodesis or autologous blood patch therapy in secondary spontaneous pneumothorax | Prof. CHAN Ken Ka Pang |
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