Approved Study Database
| Ref. No. | Scientific Title | Principal investigator |
|---|---|---|
| 2010.055 | A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Safety Study to Evaluate Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus Treated With Dutogliptin | Prof. Tomlinson Brian |
| 2009.591 | A Randomized, Double-blind, Placebo- and Comparator-Controlled, Dose Response Study of CS-1036 in Patients with Type 2 Diabetes | Prof. Tomlinson Brian |
| 2010.117 | Urinary excretion of cortisol and its metabolites: Diurnal pattern and effects of herbs products. | Prof. Tomlinson Brian |
| 2010.163 | Pharmacogenomics of nicotinic acid with laropiprant in Hong Kong Chinese patients with dyslipidemia | Prof Tomlinson Brian |
| 2008.302 | Randomized Cross-Over Clinical Bioequivalence Study on Two Oral Lithium Carbonate Formulations | Prof Tomlinson Brian |
| 2011.151 | A Phase III Multicenter, Double-Blind, Crossover Design Study to Evaluate Lipid-Altering Efficacy and Safety of Extended- Release Niacin/Laropiprant/Simvastatin Combination Tablet in Patients with Primary Hypercholesterolemia or Mixed Dyslipidemia | Prof. Tomlinson Brian |
| 2010.200 | A Randomized, Double-Blind, Placebo-controlled, Parallel-Group, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of Canagliflozin Compared With Placebo in the Treatment of Older Subjects With Type 2 Diabetes Mellitus Inadequately Controlled on Glucose Lowering Therapy | Prof. Tomlinson Brian |
| 2010.322 | Pharmacogenomics of nicotinic acid with laropiprant in Hong Kong Chinese patients with dyslipidemia | Prof Tomlinson Brian |
| 2010.360 | A Single-Dose, Open-Label, Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Oral Fampridine-PR 10 mg in Chinese, Japanese, and Caucasian Adult Healthy Volunteers | Prof. Tomlinson Brian |
| 2009.159 | A Phase III Randomized, Placebo-Controlled Clinical Trial to Study the Safety and Efficacy of the Addition of Sitagliptin (MK-0431) in Patients with Type 2 Diabetes Mellitus who Have Inadequate Glycemic Control on Combination Therapy with Metformin and Pioglitazone | Prof. Tomlinson Brian |
| 2010.399 | Phase I, open label, randomized study to examine the pharmacokinetics, safety and tolerability of different oral doses of TMC435 after single and repeated dosing in healthy Chinese subjects | Prof. Tomlinson Brian |
| 2010.600 | An Open Label, Randomized, Cross-Over Study to Investigate the Single Dose Bioequivalence of Lamotrigine Dispersible/Chewable Tablets (5mg) Compared to Lamotrigine Compressed/Standard Tablets (25mg) in Chinese Healthy Male Subjects. | Professor Tomlinson Brian |
| 2010.525 | Pharmacogenetic Analysis of the effects of Nicotinic acid and Fenofibrate on rEsidual carDiOvascular risks, liveR fat and carotid Atherosclerosis in Chinese patients treated with statins, a prospective randomized clinical trial | Prof Tomlinson Brian |
| 2010.524 | Interactions of herbs with statin drugs and potential mediation by drug transporters | Prof Tomlinson Brian |
| 2010.512 | A Randomized, Open-label, Single-dose, Two-period, Crossover Study to Demonstrate the Bioequivalence of the Fixed Dose Combination (FDC) of lamivudine and adefovir dipivoxil (100mg/10mg) to Heptodin_ (100mg) and Hepsera_ (10mg) | Professor Tomlinson Brian |
| 2009.261 | TECOS: A Randomized, Placebo Controlled Clinical Trial to Evaluate Cardiovascular Outcomes after Treatment with Sitagliptin in Patients with Type 2 Diabetes Mellitus and Inadequate Glycemic Control | Prof. TOMLINSON Brian |
| 2013.052 | Pharmacogenomics of anti-hypertensive treatment in Chinese, from unpredictable response to personalized medicine | Prof Tomlinson Brian |
| 2006.147 | Pharmacogenetics of HMG Co-A Reductase Inhibitors in Chinese Patients with Hyperlipidaemia: A Combined Pharmacodynamic Pharmacokinetic Approach | Prof. TOMLINSON Brian |
| 2013.069 | A 2-Part, Phase 2/3 Study to Assess the Safety, Tolerability and Efficacy of AMG 145 in Subjects With Homozygous Familial Hypercholesterolemia Part A - Open-label, Single-arm, Multicenter Pilot Study to Evaluate Safety, Tolerability, and Efficacy of AMG 145 in Subjects With Homozygous Familial Hypercholesterolemia Part B - Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate Safety, Tolerability and Efficacy of AMG 145 in Subjects With Homozygous Familial Hypercholesterolemia | Professor Tomlinson Brian |
| 2010.480 | SAVOR Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus A Multicenter, Randomised, Double-Blind, Placebo-Controlled Phase IV Trial to Evaluate the Effect of Saxagliptin on the Incidence of Cardiovascular Death, Myocardial Infarction or Ischaemic Stroke in Patients with Type 2 Diabetes | Professor Tomlinson Brian |
| 2007.201 | Comparison of Various Lodoz / Angiotensin Receptor Blocker Combination Regimens in the Treatment of Hypertension | Prof. TOMLINSON Brian |
| 2007.495 | Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation, Repeated Dose Study on the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AVE5026 (10, 20 and 60 mg) Given Once Daily as Subcutaneous Injections in Healthy Young Male Chinese Subjects | MD Tomlinson Brian |
| 2008.316 | Randomized Cross-Over Clinical Bioequivalence Study on Two Oral Aluminium Hydroxide Formulations | Prof Tomlinson Brian |
| 2011.616 | An Open Label, Pharmacogenetic study of Bisoprolol Treatment in Patients with Uncontrolled Essential Hypertension | Professor Tomlinson Brian |
| 2011.521 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Followed by an Open-Label Continuation Period to Assess the Safety and Efficacy of Two Different Regimens of Mipomersen in Patients with Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein Cholesterol | Prof. TOMLINSON Brian |
| 2008.153 | A 2 year extension to: A 76-week, Worldwide, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Assess the Tolerability and Efficacy of Anacetrapib When Added to Ongoing Therapy with a Statin in Patients with Coronary Heart Disease (CHD) or CHD Risk-Equivalent Disease: Reversal period extended from 12 weeks to 1-year | Professor Tomlinson Brian |
| 2009.454 | A multi-center, randomized, open-label, active-controlled study to compare the efficacy, safety and tolerability of taspoglutide (RO5073031) versus insulin glargine in insulin-naive type 2 diabetic patients inadequately controlled with metformin and sulfonylurea combination therapy | Prof. Tomlinson Brian |
| 2012.269 | A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate Safety, Tolerability and Efficacy of AMG 145 on LDL-C in Subjects with Heterozygous Familial Hypercholesterolemia | Professor Tomlinson Brian |
| 2008.152 | Evaluation of Bilberry (Vaccinium Myrtillus) Supplementation on Biomarkers of Glycaemic Control, Antioxidant Status, Inflammation and Coronary Heart Disease Risk in Type 2 Diabetic Subjects | Prof Tomlinson Brian |
| 2012.276 | A Double-blind, Randomized, Multicenter Study to Evaluate Safety and Efficacy of AMG 145, Compared With Ezetimibe, in Hypercholesterolemic Subjects Unable to Tolerate an Effective Dose of a HMG-CoA Reductase Inhibitor | Professor Tomlinson Brian |
| 2011.469 | A Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-914143 in Healthy Chinese Subjects | Prof. Tomlinson Brian |
| 2011.468 | An Open-Label, Parallel-Group, Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of BG00012 in Chinese, Japanese, and Caucasian Adult Healthy Volunteers | Professor Tomlinson Brian |
| 2012.281 | A 14 week, randomized, double-blind, multi-center, parallel group, active controlled study to evaluate the efficacy and safety of LCZ696 in comparison to olmesartan in elderly patients with essential hypertension | Prof. Tomlinson Brian |
| 2012.290 | Effect of probucol on reducing cardiovascular risk factors in Chinese patients with heterozygous familial hypercholesterolaemia | Prof Tomlinson Brian |
| 2008.485 | Assessment of Efficacy and Tolerability of Prolonged Release Nicotinic Acid in Hong Kong Patients with Dyslipidaemia | Prof Tomlinson Brian |
| 2012.331 | A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing the Impact of Additional LDL-Cholesterol Reduction on Major Cardiovascular Events When AMG 145 is Used in Combination With Statin Therapy In Patients with Clinically Evident Cardiovascular Disease | Professor Tomlinson Brian |
| 2014.089 | The effects of regular concomitant intake of grapefruit juice on the lipid-lowering effects and pharmacokinetics of statins | Prof Tomlinson Brian |
| 2012.314 | A Multicenter, Randomized, Double-Blind, Active-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of TAK-875 25 mg and 50 mg Compared to Glimepiride When Used in Combination with Metformin in Subjects with Type 2 Diabetes | Prof. TOMLINSON Brian |
| 2013.445 | SINGLE-SITE, OPEN-LABEL, RANDOMIZED, CROSS-OVER STUDY IN HEALTHY CHINESE SUBJECTS TO EVALUATE THE BIOEQUIVALENCE OF SINGLE-DOSE ROTIGOTINE TRANSDERMAL PATCH (2MG/24H) COMPARING 2 DIFFERENT FORMULATIONS | Prof Tomlinson Brian |
| 2008.503 | Predictors of Antihypertensive Response to Bisoprolol and Hydrocholorothiazide: An Open-labelled, Placebo-controlled Crossover Study to Investigate the Genetic and Biomedical Predictors of Blood Pressure Response in Chinese Patients with Mild to Moderate Hypertension | Professor Tomlinson Brian |
| 2012.330 | A randomized, double-blind, crossover study to assess the effects of LCZ696 and valsartan in Asian patients with salt-sensitive hypertension | Prof. Tomlinson Brian |
| 2011.390 | Pharmacokinetic interaction between rosuvastatin and telmisartan | Prof. TOMLINSON Brian |
| 2013.676 | Investigation of cases of drug/chemical toxicity, adverse drug reactions and interactions | Prof. TOMLINSON Brian |
| 2015.116 | Health care resource utilization analysis of paliperidone palmitate in the treatment of schizophrenia in the public health care sector of Hong Kong |
Prof. TOMLINSON Brian 湯寧信醫生 |
| 2015.115 | The impact of Illness Representations on illness management in patients with Familial Hypercholesterolemia |
Prof. TOMLINSON Brian 湯寧信 |
| 2015.448 | Retrospective pharmacogenetic analysis of dose requirement in patients on long-term stable warfarin treatment |
Prof. TOMLINSON Brian 湯寧信醫生 |
| 2015.429 | Cost effectiveness of Dapagliflozin for the treatment of Type 2 Diabetes Mellitus in Hong Kong |
Prof. TOMLINSON Brian 湯寧信醫生 |
| 2014.516 | Comparison of serum thromboxane B2 and platelet function testing with the Multiplate® device as measures of aspirin resistance in Hong Kong Chinese patients with increased cardiovascular risk with stable coronary heart disease or peripheral artery disease | Prof. TOMLINSON Brian |
| 2021.127 | The effect of culturally-adapted music therapy on preoperative anxiety, acute postoperative pain and haemodynamic readings among women with breast cancer receiving mastectomy in Nigeria: A randomised controlled trial | Ms. TOLA Yetunde Oluwafunmilayo |
| 2022.354 | An investigation of air dispersion pattern and the environmental influence of open airway suction in general ward setting and identification of a practical enclosure device for open airway suction in general ward. |
Ms. TO YUK LING 杜玉玲 |
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