Approved Study Database

Ref. No. Scientific Title Principal investigator
2018.417 Prevention of metacarpophalangeal joints structure damage in patients with psoriatic arthritis using tofacitinib Prof. TAM Lai Shan
2019.063 Effects of tight-control strategy with rosuvastatin on progression of subclinical carotid and coronary atherosclerosis in psoriatic arthritis- a prospective cohort study Prof. TAM Lai Shan
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2018.225 The APLAR Spondyloarthritis (SpA) Registry Prof. TAM Lai Shan
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2019.573 Subclinical gut inflammation and gut microbiome in axial spondyloarthritis patients in Hong Kong Prof. TAM Lai Shan
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2019.401 Immunological role of the ILC2-B lymphocyte regulatory axis in systemic lupus erythematosus Prof. TAM Lai Shan
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2019.650 Effects of tight-control strategy with and without rosuvastatin on progression of subclinical coronary and carotid atherosclerosis in psoriatic arthritis- a randomized placebo-controlled study Prof. TAM Lai Shan
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2026.275 Investigating the presence of anti-citrullinated SR-A peptide antibodies as a novel biomarker for RA Prof. TAM Lai Shan
2026.229 Prospective MRI and HR-pQCT Study of Subclinical Musculoskeletal Involvement in Psoriasis with Arthralgia and Progression to Psoriatic Arthritis Prof. Tam Lai Shan
2026.341 A Phase 1, open-label, dose-escalation study (ELEVATE-1) to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of a CD19/CD20 T-cell engager in participants with B-cell driven autoimmune rheumatic diseases (ARD) Prof. Tam Lai Shan
2026.344 Therapeutic strategy and remission of rheumatoid arthritis in the Asia-Pacific region - A multicenter real-world study Prof. Tam Lai Shan
2026.338 Treat-to-target aiming at DORIS remission and progression of subclinical atherosclerosis in systemic lupus erythematosus: a 2-year prospective cohort using high-resolution carotid ultrasound Prof. TAM Lai Shan
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2026.407 Incident comorbid cardiovascular disease in patients with rheumatoid arthritis Prof. Tam Lai Shan
2011.174 A stochastic cost-effectiveness analysis of an early inflammatory arthritis clinic in Hong Kong Prof. TAM Lai Shan
2009.215 In vivo assessment of bone microarchitecture in patients on chronic steroid therapy by high-resolution peripheral quantitative computed tomography and the finite method Prof. Tam Lai Shan
2011.031 The role of HMGB1 in the pathogenesis of systemic lupus erythematosus Professor TAM Lai Shan
2008.475 Innate pathogen recognition in systemic lupus erythematosus: Toll-like receptors and NOD-like receptors Prof Tam Lai Shan
2012.478 Vascular effects of achieving minimal disease activity iin psoriatic arthritis - a 2 year prospetive cohort study Prof. TAM Lai Shan
2010.191 Human Papillomavirus infection and cervical intraepithelial neoplasia in patients with systemic lupus erythematosus- the role of toll-like receptors Prof. TAM Lai Shan
2009.273 Diagnostic and Prognostic Values of Anti-Ceclic Citullinated Peptide Antibodies in Chinese Population with Rheumatoid Arthritis Prof. Tam Lai Shan
2009.583 Function and expression profile of the nucleotide-blinding and oligoerization domain (NOD)-2 receptors in systemic lupus erythematosus Prof. Tam Lai Shan
2010.455 A prospective case-control cost of illness studies in systemic lupus erythematosus Prof. Tam Lai Shan
2011.228 Effects of inflammation on bone loss in rheumatoid arthritis: Does inflammation affect joints and bone equally? Prof. Tam Lai Shan
2011.509 In vivo assessment of periaricular and generalized bone loss in patients with rheumatoid arthritis by high resolution peripheral quantitative computed tomography Prof. Tam Lai Shan
2011.547 The role of Receptor for Advanced Glycation End Products (RAGE) in the pathogenesis of systemic Lupus erythematosus (SLE) Professor TAM Lai Shan
2010.250 HMGB1: a danger signal molecule of the innate immune response for the immunopathogenesis of systemic lupus erythematosus Prof. TAM Lai Shan
2011.570 Bone quality in men with rheumatoid arthritis: A case-control study using the high-resolution peripheral quantitative computed tomography Prof. TAM Lai Shan
2025.247 Arresting Enthesiophyte and Erosion Progression in PsA: A 5-Year HR-pQCT Study Prof. TAM Lai Shan
2024.221 Evaluation of molecular and cellular dysregulation in systemic lupus erythematosus Prof. TAM Lai Shan
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2025.738 Cardiovascular and neurocognitive benefit of disease modifying antirheumatic drugs in patients with rheumatoid arthritis and psoriatic arthritis in Hong Kong: A large population study Prof. TAM Lai Shan
2024.661 Methotrexate versus TNF inhibition in preventing structural damage in Early Psoriatic Arthritis: A randomized trial using HR-pQCT (MeTEPsA trial) Prof. TAM Lai Shan
2025.264 Identifying the optimal erosion volume threshold for predicting rheumatoid arthritis in individuals with arthralgia: a high-resolution peripheral quantitative computed tomography study Prof. TAM Lai Shan
2025.316 Can biologic DMARD use retard syndesmophytes and facet joint arthritis progression and resolve axial inflammatory in psoriatic arthritis? A prospective follow up study using low-dose computed tomography and magnetic resonance imaging Prof. TAM Lai Shan
2024.352 A Phase 3 Randomized, Double-blind, Multi-center, Placebo-controlled Study to Evaluate the Efficacy and Safety of AR882 in Participants with Gout Prof. TAM Lai Shan
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2025.244 AI-Powered Decision-Making Model in Optimizing Belimumab and Telitacicept Treatment for SLE through Genetic and Immune Profiling Prof. TAM Lai Shan
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2024.718 REMIPPSA: REMISSION STATUS IN PSORIATIC ARTHRITIS FROM THE PATIENT’S PERSPECTIVE. A QUALITATIVE STUDY. Prof. TAM Lai Shan
2025.358 Investigating the Predictive Power of Coronary Plaque for Major Adverse Cardiovascular Events (MACE) in Psoriatic Arthritis: A 10-year Retrospective Study Prof. TAM Lai Shan
2025.258 Developing neural network based new methods for the detection and quantification of enthesiophytes and erosions in inflammatory arthritis diagnosis using high resolution peripheral quantitative computed tomography (HR-pQCT) images Prof. TAM Lai Shan
2025.432 The First Phase Study to Evaluate the Safety of In-Vivo CAR-T Therapy for Patients with Refractory Systemic Lupus Erythematosus Prof. Tam Lai Shan
2025.866 Erosion and joint space trajectories assessed using HR-pQCT in RA correlation with functional outcomes Prof. TAM Lai Shan
2023.633 Defining active and structural lesions in the sacroiliac joint and spine by MRI and their predictive utility in axial psoriatic arthritis -a prospective study Prof Tam Lai Shan
2025.008 A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of JNJ-77242113 for the Treatment of Biologic-naïve Participants with Active Psoriatic Arthritis Prof. TAM Lai Shan
2024.193 Lowest Efficacious Dose in Psoriatic Arthritis (LED PsA): A Multicentre Non-inferiority Randomized Open-Label Controlled Trial Assessing b/tsDMARDs Spacing Prof. TAM Lai Shan
2024.182 Causal machine learning models for prediction of serious infection events in inflammatory arthritis: a population-based study Prof. TAM Lai Shan
Lai Shan TAM
2025.019 Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of JNJ-77242113 for the Treatment of Biologic-experienced and Biologic-naïve Participants with Active Psoriatic Arthritis Prof. TAM Lai Shan
2015.065 Phase 3b/4 Randomized Safety Endpoint Study Of 2 Doses Of Tofacitinib In Comparison To A Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid Arthritis Prof. TAM Lai Shan
2017.295 The long term renal outcome of biopsy proven paediatric lupus nephritis - a comparison of local and overseas cohort Prof. TAM Lai Shan
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2014.343 Adaptation and validation of the Ankylosing Spondylitis Quality of Life (ASQOL) and Psoriatic Arthritis Quality of Life (PsAQOL) questionnaires in Hong Kong Prof. TAM Lai Shan
2016.366 MicroRNAs as biomarkers for predicting the effect of anti-TNF and anti-IL6 in changes of bone erosions in rheumatoid arthritis using HR-pQCT Prof. TAM Lai Shan
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2017.239 The Hong Kong Psoriatic Arthritis Screening program Prof. TAM Lai Shan
2015.334 Characterization of the potential role of interleukin-36 (IL-36) in regulating protective and pathogenic B cells in systemic lupus erythematosus Dr. TAM Lai Shan
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