Approved Study Database
| Ref. No. | Scientific Title | Principal investigator |
|---|---|---|
| 2025.657 | A Phase 1/2 Open-label Study to Investigate the Safety, Efficacy, and Pharmacokinetics of Administration of Subcutaneous Blinatumomab for the Treatment of Adults and Adolescents with Relapsed or Refractory B cell Precursor Acute Lymphoblastic Leukemia (R/R B-ALL) and Minimal Residual Disease Positive (MRD+) B-ALL |
Prof. LI Chi Kong 李志光教授 |
| 2025.621 | Novel microbiome signatures for the prediction of dementia-first versus parkinsonism-first conversion in REM sleep behavior disorder | Dr. HUANG Bei |
| 2025.661 | Unrevealing the multi-level brain reserve against age-related cognitive decline and cardiometabolic risk factors: a three-year follow-up study | Dr. LU Hanna |
| 2025.598 | Epidemiological Trend and Projections on Disease Burden in Hong Kong | Prof. HUANG Junjie |
| 2025.648 | A pilot study on the efficacy and safety of a novel synbiotic formula (SGR11) in patients with inflammatory bowel disease (IBD) | Prof. Ng Siew Chien |
| 2025.597 | Construction of diagnostic and predictive models for cirrhosis patients with complications of liver disease | Prof. Wong Grace |
| 2025.604 | Clamp catheter versus snare for Inferior Vena Cava filter retrieval: a single centre experience | Dr. LAW Wing Chung |
| 2025.588 | Exploring the Protective Role of Bacteroides intestinalis against Metabolic Dysfunction-Associated Steatotic Liver Disease | Prof. ZHANG Xiang |
| 2025.605 | A Phase I/II, Open-label, Multicenter Study of ALE.P03 (Claudin-1 Targeted Antibody-drug Conjugate) as a Monotherapy in Adult Patients with Selected Advanced or Metastatic CLDN1+ Solid Tumors | Prof. CHAN Stephen Lam |
| 2025.616 | The Effects of Transcranial Temporal Interference Stimulation to the Amygdala on Emotion Regulation and Conflict Resolution | Dr. LIU Xiaonan |
| 2025.628 | A Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Clinical Activity of GSK5764227 as Monotherapy and in Combination in Participants with Advanced Solid Tumors | Dr. LOONG Herbert Ho Fung |
| 2025.589 | A Phase 3, Randomized, Open-label, Study to Compare the Efficacy and Safety of Adjuvant MK-2870 in Combination with Pembrolizumab (MK-3475) Versus Treatment of Physician’s Choice (TPC) in Participants With Triple-Negative Breast Cancer (TNBC) Who Received Neoadjuvant Therapy and Did Not Achieve a Pathological Complete Response (pCR) at Surgery | Prof. YEO Winnie |
| 2025.777 | Speech Disfluency Analysis to Predict Cognitive Impairment --- Developing a Speech Disfluency Framework | Prof. Law Thomas |
| 2025.590 | A Phase III, Open-label, Randomised Study of Datopotamab Deruxtecan (Dato-DXd) With or Without Durvalumab Compared with Investigator’s Choice of Chemotherapy (Paclitaxel, Nab-paclitaxel or Gemcitabine + Carboplatin) in Combination With Pembrolizumab in Patients with PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05) | Prof. YEO Winnie |
| 2025.596 | Deciphering the role of ADAT2-mediated transfer RNA A-to-I modification in colorectal tumorigenesis and chemoresistance |
Dr. WONG Chi Chun Chi Chun Wong |
| 2025.668 | Knowledge on heart attack and stroke symptoms recognition in Hong Kong residents: a cross-sectional survey |
Mr. WONG Yin Fung 黃然豐 |
| 2025.619 | Review of Clinical Outcomes of Structured Non-Surgical Treatment Programme for Knee Osteoarthritis in Prince of Wales Hospital | Ms. Li Man Kuen |
| 2025.631 | AI Screening of Head CT scans for Cognitive Decline | Dr. Abrigo Jill |
| 2025.582 | Territorial big data analysis of clinicopathological parameters and clinical diagnosis, outcomes and epidemiological trends in human neoplasms | Dr. LAI Hei Ming |
| 2025.584 | Local epidemiology, prevalence and clinical outcomes of subjects with preserved ratio impaired spirometry | Dr. KO Fanny Wai San |
| 2025.583 | Clinical features and Treatment outcomes in Paediatric probable antibody-negative autoimmune encephalitis in Hong Kong | Dr. YAM Karen Kwan Ming |
| 2025.553 | Life-Style Medicine for Chronic Musculoskeletal Pain in Older People: A pragmatic, randomized controlled clinical trial | Prof. Sit Regina Wing Shan |
| 2025.549 | Biomarkers for prediction, monitoring and follow-up of pregnancy complications | Prof. POON Liona Chiu Yee |
| 2025.567 | Large language models for cancer staging based on head and neck radiology reports | Dr. WONG Matthew Lun |
| 2025.576 | Hong Kong Traditional Chinese Medicine and Western Medicine IVF-ET Treatment Model: Construction and Optimization of Medical Communication | Dr. LAM Lai Kwan |
| 2025.552 | The Effectiveness of A Multicomponent Sleep Intervention in Individuals Living in Residential Services – A Cluster Randomised Controlled Trial |
Dr. CHAN Ngan Yin Ngan Yin |
| 2025.551 | Evaluation of the effectiveness of a one-day multi-component hospital attachment program on the well-being of secondary school students in Hong Kong | Dr. CHAN Kai Tai |
| 2025.550 | The Evaluation of Safety, Tolerability, and Pharmacokinetics of ProEGCG | Prof. Wang Ronald Chi Chiu |
| 2025.566 | Cardioneural temporary pacing to achieve autonomic modulation |
Dr. TAM Tsz Kin 譚子健 |
| 2025.568 | Use of Artificial Intelligence in Building an Innovative Intestinal Ultrasound Learning Model | Dr. MAK Joyce Wing Yan |
| 2025.547 | Predictive models of dyslexia diagnosis and intervention success in early-grade primary school children: validation across cross-sectional, retrospective, and prospective longitudinal samples using EEG and behavioral data | Dr. Maurer Urs |
| 2025.586 | A Phase 1/2a, Open-Label, Multiple-Cohort, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Intravitreal (IVT) Injection of ABI-110 (AAV2.N54-VEGF Trap) in Subjects with Neovascular (Wet) Age-Related Macular Degeneration (wAMD), Including Symptomatic Macular Polypoidal Choroidal Vasculopathy (PCV) | Dr. BRELEN Marten |
| 2025.569 | Effects of SGLT2 inhibitors on benign prostatic hyperplasia progression in type 2 diabetes: a target trial emulation | Dr. LUI Juliana Nga Man |
| 2025.548 | Investigating the Non-Motor Effects on Olfaction of Deep Brain Stimulation in Patients with Parkinson’s Disease (PD) | Dr. CHAN Danny Tat Ming |
| 2025.653 | Individualised Management of Sepsis based on the construction of novel subtyping system | Dr. LING Lowell |
| 2025.630 | Left Atrial Appendage Occlusion in Dialysis Patients with Atrial Fibrillation: A Multicentre Pilot Study | Dr. SO Kent Chak Yu |
| 2025.545 | Per-oral endoscopic myotomy (POEM) for achalasia – A Prospective study on Long-term outcomes |
Dr. YIP Hon Chi 葉瀚智 |
| 2025.565 | Prognostic significance of FOXA1, FOXA2 and IL-11 in prostate cancer | Dr. YAN Kelvin |
| 2025.538 | Randomised, double-blind and placebo-controlled clinical trial on microbiome-based preventive strategies for early-onset eczema in Chinese infants |
Prof. LEUNG Ting Fan 梁廷勳 |
| 2025.564 | Complex interplay between hepatic steatosis and chronic hepatitis B on liver-related clinical outcomes |
Dr. YIP Cheuk Fung 葉卓風 |
| 2025.544 | A Randomised, Double-blind, Placebo-controlled, Multi-centre, Sequential Phase II, and Phase III Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of AZD0780 Administered for up to 52 Weeks in Participants with Dyslipidaemia (AZURE-CHINA) |
Prof. MA Ching Wan 馬青雲 |
| 2025.570 | Imaging and endovascular treatment for post-irradiation pseudoaneurysms after skull base irradiation for nasopharyngeal carcinoma | Dr. YIU Ka Sang |
| 2025.543 | Building Resilience Against Rising Temperature - The Effect of High-Intensity Interval Exercise (HIIE) on Heat Tolerance, Thermoregulatory Adaptation, and Physical Fitness: A Comparative Randomized Controlled Trial |
Prof. POON Eric Tsz Chun 潘梓竣 |
| 2025.523 | Predicting Self-Harm in Hong Kong: An AI-Driven Framework Integrating Clinical, Socioeconomic, and Environmental Data for Individual Risk Stratification | Dr. VERMA Rohit Kumar |
| 2025.522 | Validation of Diagnostic Coding for Pneumonia in Patients with Presumed Infection in the Electronic Health Record System of Hong Kong | Dr. VERMA Rohit Kumar |
| 2025.521 | Identifying the Risk Factors of Suicide Related Visits at the Emergency Department in Hong Kong | Dr. VERMA Rohit Kumar |
| 2025.537 | Effects of a sitting Tai Chi programme for chronic stroke survivors with post-stroke cognitive impairment: A pilot randomised controlled trial | Dr. ZHAO Jie |
| 2025.536 | Adopting Integrated Care for Older People (ICOPE) Framework for Assessing Intrinsic Capacity in People Aging with HIV | Dr. LUI Grace C.Y. |
| 2025.563 | A Prospective Registry for Belzutifan in the Treatment of von Hippel-Lindau (VHL) Disease | Prof. NG Chi Fai |
| 2025.542 | Air purifier and respiratory outcomes in childhood asthma in compromised housing environments: a hybrid effectiveness-implementation trial | Dr. CHAN Crystal Ying |
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