Approved Study Database
| Ref. No. | Scientific Title | Principal investigator |
|---|---|---|
| 2026.231 | A PHASE 2 INTERVENTIONAL STUDY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY IN PARTICIPANTS WITH PREVIOUSLY UNTREATED TRANSFORMED SMALL CELL LUNG CANCER | Prof. MOK Tony Shu Kam |
| 2026.227 | Personalized Prediction of Toxicities and Clinical Outcomes of Prostate Conventional and Moderately Hypofractionated Radiotherapy – A Retrospective Study | Dr. Wong Kenneth Chun Wai |
| 2026.264 | Estimating and Translating the Real-World Effectiveness of Nirsevimab to Inform RSV Prevention Policy in Hong Kong | Prof. CAO Lirong |
| 2026.220 | Quantitative Assessment of Physical Activity in Children with and without Adolescent Idiopathic Scoliosis Using Wearable Technology |
Dr. Kwan Cheuk Kin 關棹鍵 |
| 2026.226 | Development of a Territory-Wide Clinical Database on Systemic Lupus Erythematosus and Lupus Nephritis in Hong Kong | Dr. SO Ho |
| 2026.228 | The "False-High" Transferrin Saturation Phenotype: A Retrospective Review of Elevated TSAT Caused by Hypotransferrinaemia in Maintenance Haemodialysis Patients in Hong Kong. | Dr. CHAN Anthony Ting Pong |
| 2026.230 | A Phase 3, Randomized, Open-label Study Comparing Efficacy and Safety of Sacituzumab Tirumotecan (sac-TMT, MK-2870) as a Monotherapy and in Combination with Pembrolizumab (MK-3475) Versus Treatment of Physician’s Choice in Participants With Previously Untreated Locally Recurrent Unresectable or Metastatic Triple-Negative Breast Cancer Expressing PD-L1 at CPS Less than 10 (TroFuse-011) | Prof. YEO Winnie |
| 2026.285 | Phase IV post-market, real-world data on the use of adjunctive or monotherapy with brivaracetam in patients with generalized or focal epilepsy | Dr. LEUNG Howan |
| 2026.292 | Computational Vaccinology of Mpox Virus: VE-GD–Based Prediction of Vaccine Effectiveness and Antigen Target Identification (猴痘病毒计算疫苗学研究：基于VE-GD模型的效力动态预测与抗原识别) |
Dr. CAO LIRONG Liz CAO |
| 2026.390 | A Cross-Sectional Analysis of the Association Between MASLD Severity and Categories of CAD Severity | Dr. LI Po Yi |
| 2026.212 | A Cost-Effective Model for Children Myopia Detection, Prevention, and Treatment | Prof. YAM Jason Cheuk Sing |
| 2026.255 | A 5-year prospective study of multimodal deep phenotyping with digital measurements, multi-omics, and neuroimaging biomarkers in prodromal and early stages of alpha-synucleinopathy neurodegeneration | Prof. Wing Yun Kwok |
| 2026.229 | Prospective MRI and HR-pQCT Study of Subclinical Musculoskeletal Involvement in Psoriasis with Arthralgia and Progression to Psoriatic Arthritis | Prof. Tam Lai Shan |
| 2026.187 | A prospective study of clinical responses to Lecanemab in patients with early Alzheimer disease in Hong Kong | Prof. Kwok Timothy |
| 2026.191 | Oral bacterial immunotherapy (Uromune) in long-term indwelling Foley catheter patients: a self-controlled pilot study for prevention of catheter-associated urinary tract infection (CAUTI) with microbiome and immune correlates | Dr. LIU Alex Qinyang |
| 2026.190 | Endoscopic Duodenal-jejunal Bypass Sleeve for Treatment of Obesity and Metabolic Syndrome – A Multicenter Pilot Study |
Dr. NG STEPHEN KA KEI 吳家琦 |
| 2026.207 | Data collection for development of augmented reality (AR) for visual assistance and image-guided navigation in laparoscopic and robotic abdominal surgery |
Dr. Yip Hon Chi 葉瀚智 |
| 2026.186 | Epigenetic and proteomic biomarkers of healthy ageing - validation in a cross-sectional study of ageing | Prof. KWOK Timothy Chi Yui |
| 2026.182 | The efficacy and safety of female autologous platelet‐rich plasma (PRP) co-incubation with sperm during the intrauterine insemination (IUI) cycles: A prospective, randomized controlled trial. | Prof. CHUNG Jacqueline Pui Wah |
| 2026.206 | A Visual Mapping Approach to CT Scoring in Chronic Rhinosinusitis: A Prospective Crossover Study of Efficacy and Reliability | Dr. Yeung David |
| 2026.218 | 老年急性上呼吸道感染抗病毒治疗的成本效果与策略优化 Cost-Effectiveness and Strategy Optimization of Antiviral Therapy for Acute Upper Respiratory Tract Infections in Older Adults | Dr. WEI Yuchen |
| 2026.177 | Neuroscience for Better Living: Research Impact the Society |
Dr. Ning Xiaoran 寧曉然 |
| 2026.167 | Therapeutic Outcomes of Single Dose Platelet-Rich Plasma Injection for Post-viral Olfactory Dysfunction: A Long-term Prospective Study in a Chinese Population | Dr. Yeung David Chun Man |
| 2026.205 | Epigenetic and proteomic biomarkers of healthy ageing | Prof. Kwok Timothy Chi Yui |
| 2026.196 | Prevalence and Prognostic Significance of the FIFA (Frailty, Inflammation, Fluid-Overload, and Atherosclerosis) Complex in Incident Peritoneal Dialysis Patients |
Prof. SZETO Cheuk Chun 司徒卓俊 |
| 2026.210 | An AI-driven Multimodal Digital Clock Drawing Test System for the Screening of Mild Cognitive Impairment and Dementia: Development and Validation Study | Prof. KWOK Timothy |
| 2026.175 | Clinical trial to evaluate chemical modifications on microbiome-derived cell-free RNA as novel biomarkers for early diagnosis of colorectal cancer (CRC) in the Chinese population | Prof. NG Simon |
| 2026.195 | Glycemic assessment based on continuous glucose monitoring and clinical outcomes in people with diabetes on peritoneal dialysis: a multi-centered prospective study | Dr. Chow Elaine |
| 2026.176 | The combination of Aortic Dissection Detection Risk Score with D-dimer to rule-out acute aortic syndrome: multicentre prospective study in emergency departments | Prof. GRAHAM Colin |
| 2026.172 | Effects of Tai Chi combined with Cognitive Behavioral Therapy for Insomnia (CBT-I) on chronic insomnia in older adults: A randomized controlled trial. | Dr. YU Pak Hung |
| 2026.180 | A Phase III, multi-center, open-label, randomised, controlled trial of intravenous obrixtamig in combination with carboplatin and etoposide vs. carboplatin and etoposide as first-line therapy in DLL3-positive patients with unresectable locally advanced or metastatic extrapulmonary neuroendocrine carcinomas | Prof. CHAN Stephen Lam |
| 2026.204 | Long-term Evolution of Patients with Hepatocellular Carcinoma Treated with Immunotherapy and Who Achieve Objective Response: The LEO-HCC study | Prof. Chan Stephen Lam |
| 2026.189 | A Clinically-Oriented Antimicrobial Resistance Surveillance Network for Healthcare-associated infections (ACORN-HAI-LITE) | Prof. LING Lowell |
| 2026.185 | Immunogenic epitopes from the non-coding genome as tumor-specific antigens for drug development against childhood acute myeloid leukemia | Prof. LEUNG Kam Tong |
| 2026.267 | Histotripsy for treatment of bone and soft tissue tumours |
Prof. Griffith James 高士進 |
| 2026.287 | Evaluating safety, effectiveness, and healthcare resource utilization of novel and conventional therapies in the treatment and prevention of CKD and AKI | Dr. NG Kit Chung |
| 2026.184 | ROSETTA Lung-201: A Randomized, Multicenter, Open-label Phase 3 study of Pumitamig Monotherapy Compared to Durvalumab in Participants with Unresectable Stage III NSCLC Without Progression After Platinum-based Concurrent Chemoradiation Therapy. | Dr. LI Siu Ching |
| 2026.192 | Effects of dance-based multimodal exercise programme for managing chemotherapy-induced peripheral neuropathy in patients with solid tumors: A pilot randomized controlled study | Ms. Lau Ka Yan |
| 2026.163 | Combating Aging-Associated Sarcopenia: From Knowledge Discovery to Intervention Testing | Prof. Wang Huating |
| 2026.156 | A retrospective study on the epidemiology, clinical presentation and outcome of different neuro-ophthalmic diseases in Hong Kong | Dr. MAK Chun Yue |
| 2026.155 | Phosphodiesterase type 5 inhibitor combination therapy and cardiovascular outcomes in men with late-onset hypogonadism and erectile dysfunction undergoing testosterone replacement therapy | Prof. NG Chi Fai |
| 2026.371 | Positional CT of knees of normal subjects |
Prof. Griffith James 高士進 |
| 2026.193 | A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Intravenously Administered PYC-003, a Peptide-Phosphorodiamidate Morpholino Oligonucleotide Conjugate, in Healthy Adult Participants and Adult Participants with Confirmed PKD1 Mutation-Associated Autosomal Dominant Polycystic Kidney Disease | Prof. SZETO Cheuk Chun |
| 2026.197 | Bridging the Divide: Hybrid Perioperative Physiotherapy Care Model for Enhanced Recovery After Surgery (ERAS) in Adolescent Idiopathic Scoliosis Patients Receiving Posterior Spinal Fusion | Miss Hui Wing Hei |
| 2026.203 | Automated MRI-Based Segmentation of Multiple Sclerosis Lesions | Prof. So Tiffany Yuen Tung |
| 2026.165 | Preventing invasive Staphylococcus aureus infection in patients on dialysis through machine learning derived risk prediction score and targeted decolonization | Dr. LAI Christopher Koon Chi |
| 2026.158 | A NOVEL MULTIPLEX ELISA ASSAY FOR EVALUATING AND SURVEILLING PATIENTS WITH UPPER TRACT UROTHELIAL CARCINOMA (UTUC) | Dr. TEOH Jeremy Yuen Chun |
| 2026.222 | A Phase 1, Randomized, Double-Blinded, Placebo-Controlled Study to Evaluate Safety, Tolerability, Pharmacokinetics, And Preliminary Efficacy of Single and Multiple Ascending Doses of IB-001 in Healthy Participants and Participants with Chronic Hepatitis B | Prof. Wong Grace Lai Hung |
| 2026.181 | Levosimendan on Myocardial Injury after Noncardiac Surgery: Protocol for a Double-blinded, Placebo-controlled, Randomized Pilot Feasibility Trial | Prof. WONG Henry M.K. |
| 2026.150 | Retrospective Review of Surgical Outcomes in Patients with Spinal Metastasis | Dr. Lau Cyrus Tsun Kit |
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